Besifloxacin

Modify Date: 2024-01-05 20:24:25

Besifloxacin Structure
Besifloxacin structure
Common Name Besifloxacin
CAS Number 141388-76-3 Molecular Weight 393.84
Density 1.5±0.1 g/cm3 Boiling Point 607.0±55.0 °C at 760 mmHg
Molecular Formula C19H21ClFN3O3 Melting Point N/A
MSDS N/A Flash Point 320.9±31.5 °C

 Use of Besifloxacin


Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity[1].

 Names

Name 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid
Synonym More Synonyms

 Besifloxacin Biological Activity

Description Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity[1].
Related Catalog
Target

Bacteria[1]

References

[1]. Zhang JZ, et al. Besifloxacin, a novel fluoroquinolone antimicrobial agent, exhibits potent inhibition of pro-inflammatory cytokines in human THP-1 monocytes. J Antimicrob Chemother. 2008;61(1):111-116.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 607.0±55.0 °C at 760 mmHg
Molecular Formula C19H21ClFN3O3
Molecular Weight 393.84
Flash Point 320.9±31.5 °C
Exact Mass 393.125549
PSA 88.56000
LogP 1.91
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.649
Storage condition -20°C

 Safety Information

Hazard Codes Xn

 Synonyms

QCR-76
7-[(3R)-3-Amino-1-azepanyl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
3-Quinolinecarboxylic acid, 7-[(3R)-3-aminohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-
Besifloxacin [INN]
BFE2NBZ7NX
UNII-BFE2NBZ7NX
Besivance
(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Besifloxacin