(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine

Modify Date: 2024-01-10 16:47:15

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure
(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine structure
Common Name (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine
CAS Number 141781-17-1 Molecular Weight 589.85000
Density 1.22g/cm3 Boiling Point N/A
Molecular Formula C24H43N3O8SSi2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 1-[(5R,6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.22g/cm3
Molecular Formula C24H43N3O8SSi2
Molecular Weight 589.85000
Exact Mass 589.23100
PSA 160.58000
LogP 5.24690
Index of Refraction 1.541

 Synthetic Route

~85%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Camarasa; Balzarini; De Clercq Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3029 - 3032

~74%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995

~%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Camarasa; Balzarini; De Clercq Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3029 - 3032

~%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995

~%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995

~%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995

~%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995

~%

(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine Structure

(2',5'-bis-O-(t...

CAS#:141781-17-1

Literature: Perez-Perez; San-Felix; Camarasa; Balzarini; De Clercq Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3029 - 3032

 Synonyms

Tsao-T
C24H43N3O8SSi2
2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)pyrimidine
2,4(1H,3H)-Pyrimidinedione,1-(4-amino-9-(((1,1-dimethylethyl)dimethylsilyl)oxy)-6-((((1,1-dimethylethyl)dimethylsilyl)oxy)methyl)-1,7-dioxa-2-thiaspiro(4,4)non-3-en-8-yl)-5-methyl-,S,S-dioxide. (5R-(5alpha,6beta,8beta,9alpha))
3qo9