RG 14893

Modify Date: 2024-04-06 16:48:52

RG 14893 Structure
RG 14893 structure
Common Name RG 14893
CAS Number 141835-49-6 Molecular Weight 453.52900
Density 1.231g/cm3 Boiling Point 678.5ºC at 760mmHg
Molecular Formula C29H27NO4 Melting Point N/A
MSDS N/A Flash Point 364.1ºC

 Use of RG 14893


RG 14893 is a high affinity, competitive, orally active leukotriene B4 receptor antagonist[1].

 Names

Name 4-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-8-phenylmethoxynaphthalene-2-carboxylic acid

 Chemical & Physical Properties

Density 1.231g/cm3
Boiling Point 678.5ºC at 760mmHg
Molecular Formula C29H27NO4
Molecular Weight 453.52900
Flash Point 364.1ºC
Exact Mass 453.19400
PSA 66.84000
LogP 5.36060
Vapour Pressure 2.45E-19mmHg at 25°C
Index of Refraction 1.647

 Synthetic Route

~89%

RG 14893 Structure

RG 14893

CAS#:141835-49-6

Literature: Chan, Wan K.; Huang, Fu-Chih; Morrissette, Matthew M.; Warus, James D.; Moriarty, Kevin J.; Galemmo, Robert A.; Dankulich, William D.; Poli, Gregory; Sutherland, Charles A. Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3756 - 3768

 Precursor & DownStream

Precursor  1

DownStream  0