16-Hydroxycleroda-3,13-dien-15,16-olide

Modify Date: 2024-01-02 14:00:59

16-Hydroxycleroda-3,13-dien-15,16-olide Structure
16-Hydroxycleroda-3,13-dien-15,16-olide structure
 Common Name 16-Hydroxycleroda-3,13-dien-15,16-olide
CAS Number 141979-19-3 Molecular Weight 318.45
Density N/A Boiling Point N/A
Molecular Formula C20H30O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 16-Hydroxycleroda-3,13-dien-15,16-olide


16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy[1].

 Names

Name 16-Hydroxycleroda-3,13-dien-15,16-olide

 16-Hydroxycleroda-3,13-dien-15,16-olide Biological Activity

Description 16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy[1].
Related Catalog
References

[1]. Po-Kai Huang, et al. Polyalthia Clerodane Diterpene Potentiates Hypoglycemia via Inhibition of Dipeptidyl Peptidase 4. Int J Mol Sci. 2019 Jan 27;20(3):530.

 Chemical & Physical Properties

Molecular Formula C20H30O3
Molecular Weight 318.45
Storage condition 2-8℃
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Chemsrc provides 16-Hydroxycleroda-3,13-dien-15,16-olide(CAS#:141979-19-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 16-Hydroxycleroda-3,13-dien-15,16-olide are included as well.>> amp version: 16-Hydroxycleroda-3,13-dien-15,16-olide

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