ML298
Modify Date: 2024-04-03 13:05:01
ML298 structure
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Common Name | ML298 | ||
|---|---|---|---|---|
| CAS Number | 1426916-02-0 | Molecular Weight | 432.439 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 650.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C22H23F3N4O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 347.2±31.5 °C | |
Use of ML298ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM); decreases invasive migration in U87-MG glioblastoma cells; has an attractive DMPK profile, making it an attractive tool compound to further dissect PLD2 function in multiple cellular and in vivo environments. |
| Name | 3,4-Difluoro-N-{2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl}benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM); decreases invasive migration in U87-MG glioblastoma cells; has an attractive DMPK profile, making it an attractive tool compound to further dissect PLD2 function in multiple cellular and in vivo environments. |
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| References | References 1. O'Reilly MC, et al. J Med Chem. 2013 Mar 28;56(6):2695-9. 2. Scott SA, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target Phospholipase |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 650.5±55.0 °C at 760 mmHg |
| Molecular Formula | C22H23F3N4O2 |
| Molecular Weight | 432.439 |
| Flash Point | 347.2±31.5 °C |
| Exact Mass | 432.177307 |
| LogP | 1.70 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.620 |
| RIDADR | NONH for all modes of transport |
|---|
| 3,4-Difluoro-N-{2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl}benzamide |
| Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: ML298
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tom
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: ML298
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: ML298
- Price: $600.0/100mg $1100.0/250mg $2200.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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