hGGPPS-IN-1

Modify Date: 2024-01-08 10:57:14

hGGPPS-IN-1 structure	Common Name	hGGPPS-IN-1
	CAS Number	1429012-38-3	Molecular Weight	401.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₃N₃O₆P₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of hGGPPS-IN-1

hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo[1].

Name	hGGPPS-IN-1

Description	hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Lee HF, et al. Synthesis and Evaluation of Structurally Diverse C-2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase. J Med Chem. 2022;65(3):2471-2496.

Molecular Formula	C₁₃H₁₃N₃O₆P₂S
Molecular Weight	401.27

DC Chemicals Limited
China
Product Name: hGGPPS-IN-1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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