3-hydroxy Octanoic Acid

Modify Date: 2024-01-09 17:35:47

3-hydroxy Octanoic Acid Structure
3-hydroxy Octanoic Acid structure
Common Name 3-hydroxy Octanoic Acid
CAS Number 14292-27-4 Molecular Weight 160.21100
Density 1.046 g/cm3 Boiling Point 288.3ºC at 760 mmHg
Molecular Formula C8H16O3 Melting Point N/A
MSDS N/A Flash Point 142.4ºC

 Use of 3-hydroxy Octanoic Acid


3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

 Names

Name 3-hydroxyoctanoic acid
Synonym More Synonyms

 3-hydroxy Octanoic Acid Biological Activity

Description 3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
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 Chemical & Physical Properties

Density 1.046 g/cm3
Boiling Point 288.3ºC at 760 mmHg
Molecular Formula C8H16O3
Molecular Weight 160.21100
Flash Point 142.4ºC
Exact Mass 160.11000
PSA 57.53000
LogP 1.40230

 Synonyms

3-HYDROXY C8:0 ACID
3-Hydroxy-caprylsaeure
3-hydroxy-octanoic acid
3-Hydroxycaprylic acid
3-HYDROXYOCTANOIC ACID