14292-27-4

14292-27-4 structure

Name: 3-hydroxy Octanoic Acid
Chemical Name: 3-hydroxyoctanoic acid
CAS Number: 14292-27-4
Molecular Formula: C₈H₁₆O₃
Molecular Weight: 160.21100
Catalog: Research Areas Others
Create Date: 2018-07-06 18:07:08
Modify Date: 2024-01-09 17:35:47
3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

Name	3-hydroxyoctanoic acid
Synonyms	3-HYDROXY C8:0 ACID 3-Hydroxy-caprylsaeure 3-hydroxy-octanoic acid 3-Hydroxycaprylic acid 3-HYDROXYOCTANOIC ACID

Description	3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
Related Catalog	Research Areas >> Others