2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate

Modify Date: 2024-01-05 09:16:25

2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate Structure
2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate structure
Common Name 2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate
CAS Number 143157-27-1 Molecular Weight 472.39500
Density 1.49±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C23H18F2N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name [(2R,5R)-3-benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4,4-difluorooxolan-2-yl]methyl benzoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.49±0.1 g/cm3(Predicted)
Molecular Formula C23H18F2N2O7
Molecular Weight 472.39500
Exact Mass 472.10800
PSA 116.95000
LogP 2.56420

 Synthetic Route

~83%

2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate Structure

2′,2′-Difluoro-...

CAS#:143157-27-1

Literature: ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija Patent: US2013/165400 A1, 2013 ; Location in patent: Paragraph 0418; 0419 ;

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2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate Structure

2′,2′-Difluoro-...

CAS#:143157-27-1

Literature: DABUR PHARMA LIMITED Patent: WO2006/92808 A1, 2006 ; Location in patent: Page/Page column 44; 45 ;

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2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate Structure

2′,2′-Difluoro-...

CAS#:143157-27-1

Literature: SICOR INC. Patent: WO2006/63105 A1, 2006 ; Location in patent: Page/Page column 11-12 ;

~%

2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate Structure

2′,2′-Difluoro-...

CAS#:143157-27-1

Literature: Chou; Heath; Patterson; Poteet; Lakin; Hunt Synthesis, 1992 , # 6 p. 565 - 570

~%

2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate Structure

2′,2′-Difluoro-...

CAS#:143157-27-1

Literature: ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija Patent: US2013/165400 A1, 2013 ;

 Synonyms

3,5-Dibenzoate-2,2-difluorouridine
21-deoxy-21,21-difluoro-3,5-di-O-benzoyl-uridine
2'-deoxy-2',2'-difluoro-3,5-dibenzoate-uridine
2'-deoxy-2',2'-difluorouridine-3',5'-dibenzoate
2',2'-Difluoro-2'-deoxyuridine 3',5'-Dibenzoate