Cnidicin

Modify Date: 2024-01-09 11:00:33

Cnidicin Structure
Cnidicin structure
Common Name Cnidicin
CAS Number 14348-21-1 Molecular Weight 354.396
Density 1.2±0.1 g/cm3 Boiling Point 519.0±50.0 °C at 760 mmHg
Molecular Formula C21H22O5 Melting Point N/A
MSDS N/A Flash Point 267.7±30.1 °C

 Use of Cnidicin


Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1].

 Names

Name cnidicin
Synonym More Synonyms

 Cnidicin Biological Activity

Description Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1].
Related Catalog
In Vitro Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM)[1].
References

[1]. Ryu SY, et al. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Planta Med. 2001 Mar;67(2):172-4.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 519.0±50.0 °C at 760 mmHg
Molecular Formula C21H22O5
Molecular Weight 354.396
Flash Point 267.7±30.1 °C
Exact Mass 354.146729
PSA 61.81000
LogP 6.07
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.580
Storage condition 2-8℃

 Synonyms

7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-bis[(3-methyl-2-buten-1-yl)oxy]-
4,9-Bis[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one