Hydroquinidine

Modify Date: 2024-01-02 10:56:08

Hydroquinidine Structure
Hydroquinidine structure
 Common Name Hydroquinidine
CAS Number 1435-55-8 Molecular Weight 326.433
Density 1.2±0.1 g/cm3 Boiling Point 498.4±30.0 °C at 760 mmHg
Molecular Formula C20H26N2O2 Melting Point 169-170 ºC
MSDS Chinese USA Flash Point 255.2±24.6 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Hydroquinidine


Hydroquinidine is an antiarrhythmic agent.

 Names

Name Hydroquinidine
Synonym More Synonyms

 Hydroquinidine Biological Activity

Description Hydroquinidine is an antiarrhythmic agent.
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 498.4±30.0 °C at 760 mmHg
Melting Point 169-170 ºC
Molecular Formula C20H26N2O2
Molecular Weight 326.433
Flash Point 255.2±24.6 °C
Exact Mass 326.199432
PSA 45.59000
LogP 3.77
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.626

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MX3016000
CHEMICAL NAME :
Hydroquinidine
CAS REGISTRY NUMBER :
1435-55-8
LAST UPDATED :
199607
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H26-N2-O2
MOLECULAR WEIGHT :
326.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions Behavioral - headache Cardiac - EKG changes not diagnostic of specified effects
REFERENCE :
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 18,659,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,184,1945

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 20/21/22
Safety Phrases 36/37-36
RIDADR UN 1544
WGK Germany 3
RTECS MX3016000
Packaging Group III
HS Code 2933990090

 Synthetic Route

Quinidine structure

Quinidine

CAS#:56-54-2

~%

Hydroquinidine Structure

Hydroquinidine

CAS#:1435-55-8

Literature: Chemische Berichte, , vol. 45, p. 3317

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

EINECS 215-862-5
HYDROQUINIDINE
(9S)-6'-Methoxy-10,11-dihydrocinchonan-9-ol
MFCD00135599
(+)-Dihydroquinidine
(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
dihydroquinidine
hydroconchinine
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Related Compounds: More...
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