3-(2-(2-Methoxyethoxy)ethoxy)propanehydrazide

Modify Date: 2024-01-09 12:44:34

3-(2-(2-Methoxyethoxy)ethoxy)propanehydrazide Structure
3-(2-(2-Methoxyethoxy)ethoxy)propanehydrazide structure
Common Name 3-(2-(2-Methoxyethoxy)ethoxy)propanehydrazide
CAS Number 1442104-10-0 Molecular Weight 206.24
Density N/A Boiling Point N/A
Molecular Formula C8H18N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-(2-(2-Methoxyethoxy)ethoxy)propanehydrazide


m-PEG3-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG3-Hydrazide

  Biological Activity

Description m-PEG3-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C8H18N2O4
Molecular Weight 206.24
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