Licochalcone C
Modify Date: 2024-01-03 09:08:04
Licochalcone C structure
|
Common Name | Licochalcone C | ||
|---|---|---|---|---|
| CAS Number | 144506-14-9 | Molecular Weight | 338.397 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 536.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H22O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 188.4±23.6 °C | |
Use of Licochalcone CLicochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. |
| Name | (E)-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. |
|---|---|
| Related Catalog | |
| Target |
IC50: <100 nM (α-glucosidase), 92.43 μM (PTP1B)[1]. |
| In Vitro | Licochalcone C could inhibit α- glucosidase, with IC50s of <100 nM and 92.43 μM for α- glucosidase and PTP1B, respectively[1]. It is also indicated that Licochalcone C induces T24 cell apoptosis in a concentration‑dependent manner. Licochalcone C treatment reduces the levels of the anti‑apoptotic mRNAs (Bcl-2, Bcl-w and Bcl-XL) and increases expression of the pro-apoptotic mRNAs (Bax and Bim). The Bcl-2 family inhibitor (ABT-737) reduces apoptosis induced by licochalcone C in T24 cells[2]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 536.1±50.0 °C at 760 mmHg |
| Molecular Formula | C21H22O4 |
| Molecular Weight | 338.397 |
| Flash Point | 188.4±23.6 °C |
| Exact Mass | 338.151794 |
| PSA | 66.76000 |
| LogP | 5.33 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.622 |
| Storage condition | 2-8C |
| 2-Propen-1-one, 3-[4-hydroxy-2-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-1-(4-hydroxyphenyl)-, (2E)- |
| (2E)-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
| Y0122 |
| (2E)-3-[4-Hydroxy-2-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one |
| Licochalcone C |
| UNII-P1H7W3812O |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Licochalcone C
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Licochalcone C
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Licochalcone C
- Price: ￥2948.0/10mg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Licochalcone C
- Price: $280.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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Price: ￥1900/1 mg
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