Hematoporphyrin

Modify Date: 2024-01-02 16:54:31

Hematoporphyrin Structure
Hematoporphyrin structure
Common Name Hematoporphyrin
CAS Number 14459-29-1 Molecular Weight 598.689
Density 1.3±0.1 g/cm3 Boiling Point 1179.7±65.0 °C at 760 mmHg
Molecular Formula C34H38N4O6 Melting Point 172.5°C
MSDS N/A Flash Point 667.3±34.3 °C

 Use of Hematoporphyrin


Hematoporphyrin (Hematoporphyrin IX) is a substrate for affinity chromatography of heme-binding proteins.

 Names

Name hematoporphyrin
Synonym More Synonyms

 Hematoporphyrin Biological Activity

Description Hematoporphyrin (Hematoporphyrin IX) is a substrate for affinity chromatography of heme-binding proteins.
Related Catalog
In Vitro Hematoporphyrin is used for affinity chromatography of heme-binding proteins. Hematoporphyrin is used in the characterization and synthesis of hematoporphyrin- and hematin-agarose [1].
References

[1]. Olsen, K.W., Affinity chromatography of heme-binding proteins: synthesis and characterization of hematin- and hematoporphyrin-agarose. Methods Enzymol, 1986. 123: p. 324-31.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1179.7±65.0 °C at 760 mmHg
Melting Point 172.5°C
Molecular Formula C34H38N4O6
Molecular Weight 598.689
Flash Point 667.3±34.3 °C
Exact Mass 598.279114
PSA 171.36000
LogP 5.95
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.642
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TS5500000
CHEMICAL NAME :
2,18-Porphinedipropionic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-
CAS REGISTRY NUMBER :
14459-29-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C34-H38-N4-O6
MOLECULAR WEIGHT :
598.76
WISWESSER LINE NOTATION :
T D5 I5 N5-16-5 A D- I- N- AM D-N I-M N-NJ EYQ F J K2VQ O2VQ TYQ U

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
307 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
1 mg/L
REFERENCE :
TUMOAB Tumori. (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan, Italy) V.1- 1911- Volume(issue)/page/year: 67,183,1981

 Safety Information

Safety Phrases 22-24/25
WGK Germany 3
RTECS TS5500000

 Synthetic Route

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Hematoporphyrin Structure

Hematoporphyrin

CAS#:14459-29-1

Literature: Australian Journal of Chemistry, , vol. 33, # 3 p. 585 - 597

~%

Hematoporphyrin Structure

Hematoporphyrin

CAS#:14459-29-1

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 142, p. 141,151, 145<1925>202,214

~%

Hematoporphyrin Structure

Hematoporphyrin

CAS#:14459-29-1

Literature: Justus Liebigs Annalen der Chemie, , vol. 468, p. 98,108

~%

Hematoporphyrin Structure

Hematoporphyrin

CAS#:14459-29-1

Literature: Justus Liebigs Annalen der Chemie, , vol. 468, p. 98,108

~%

Hematoporphyrin Structure

Hematoporphyrin

CAS#:14459-29-1

Literature: Australian Journal of Chemistry, , vol. 33, # 3 p. 585 - 597

 Synonyms

EINECS 238-450-7
Photodyn
HematoporphyrineBase
MFCD00005077
3,3'-[7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphyrindiyl]dipropanoic acid
1,3,5,8-Tetramethyl-2,4-bis(a-hydroxyethyl)porphine-6,7-dipropionic Acid
21H,23H-Porphine-2,18-dipropanoic acid, 8,13-bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-
3,3'-[7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl]dipropanoic acid
Hematoporphyrin
Sensibion
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