(+)-Dehydroabiethylamine

Modify Date: 2024-01-02 09:45:28

(+)-Dehydroabiethylamine structure	Common Name	(+)-Dehydroabiethylamine
	CAS Number	1446-61-3	Molecular Weight	285.467
	Density	1.0±0.1 g/cm3	Boiling Point	382.9±11.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₁N	Melting Point	44.50℃
	MSDS	Chinese USA	Flash Point	156.7±9.1 °C
	Symbol	GHS07	Signal Word	Warning

Use of (+)-Dehydroabiethylamine

Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity[1].

Name	dehydroabietylamine
Synonym	More Synonyms

Description	Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PDHK Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB1 CB2
References	[1]. Merarchi M, et, al. A Brief Overview of the Antitumoral Actions of Leelamine. Biomedicines. 2019 Jul 19;7(3):53.

Density	1.0±0.1 g/cm3
Boiling Point	382.9±11.0 °C at 760 mmHg
Melting Point	44.50℃
Molecular Formula	C₂₀H₃₁N
Molecular Weight	285.467
Flash Point	156.7±9.1 °C
Exact Mass	285.245636
PSA	26.02000
LogP	6.40
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.528
Storage condition	Desiccate at +4°C

(+)-Dehydroabiethylamine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP8701000

CHEMICAL NAME :: Podocarpa-8,11,13-trien-15-amine, 13-isopropyl-

CAS REGISTRY NUMBER :: 1446-61-3

BEILSTEIN REFERENCE NO. :: 3084620

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H31-N

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C: Corrosive;Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TP8701000
HS Code	3806900090

1-Phenanthrenec...

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(+)-Dehydroabie...

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Literature: Svensk Kemisk Tidskrift, , vol. 66, p. 316,321

dehydroabietic acid

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(+)-Dehydroabie...

CAS#:1446-61-3

Literature: Zhurnal Organicheskoi Khimii, , vol. 9, p. 756 - 758,778 - 780

N/A

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(+)-Dehydroabie...

CAS#:1446-61-3

Literature: Tetrahedron, , vol. 53, # 42 p. 14355 - 14368

Precursor 2
CAS#:31148-95-5 1-Phenanthrenec... CAS#:1740-19-8 dehydroabietic acid
DownStream 1
CAS#:115269-93-7 DEHYDROABIETHYL...

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synthesis of Tertiary and Quaternary Amine Derivatives from Wood Resin as Chiral NMR Solvating Agents.

Molecules 20 , 20873-86, (2015)

Chiral tertiary and quaternary amine solvating agents for NMR spectroscopy were synthesized from the wood resin derivative (+)-dehydroabietylamine (2). The resolution of enantiomers of model compounds...

Leelamine hydrochloride,(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanaminehydrochloride

EINECS 215-899-7

MFCD00213430

(+)-DehydroabietylaMine [Optical Resolving Agent]

Dehydroabiethylamine