HUHS015
Modify Date: 2024-01-20 17:41:53
HUHS015 structure
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Common Name | HUHS015 | ||
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| CAS Number | 1453097-13-6 | Molecular Weight | 318.372 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 585.2±42.0 °C at 760 mmHg | |
| Molecular Formula | C19H18N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 307.7±27.9 °C | |
Use of HUHS015HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. [1] |
| Name | 4-Benzyl-3-methyl-1-(5-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-5-ol |
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| Synonym | More Synonyms |
| Description | HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. [1] |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 585.2±42.0 °C at 760 mmHg |
| Molecular Formula | C19H18N4O |
| Molecular Weight | 318.372 |
| Flash Point | 307.7±27.9 °C |
| Exact Mass | 318.148071 |
| LogP | 4.72 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.689 |
| Storage condition | 2-8℃ |
| 1H-Pyrazol-5-ol, 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)- |
| 4-Benzyl-3-méthyl-1-(6-méthyl-1H-benzimidazol-2-yl)-1H-pyrazol-5-ol |
| 4-Benzyl-3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-5-ol |
| 4-Benzyl-3-methyl-1-(5-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-5-ol |
| 4-Benzyl-3-méthyl-1-(5-méthyl-1H-benzimidazol-2-yl)-1H-pyrazol-5-ol |
| 1H-Pyrazol-5-ol, 3-methyl-1-(5-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)- |
| HUHS015 |