Latanoprost lactone diol
Latanoprost lactone diol structure
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Common Name | Latanoprost lactone diol | ||
|---|---|---|---|---|
| CAS Number | 145667-75-0 | Molecular Weight | 304.381 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 523.0±35.0 °C at 760 mmHg | |
| Molecular Formula | C18H24O4 | Melting Point | 69-71ºC | |
| MSDS | N/A | Flash Point | 190.3±19.4 °C | |
Use of Latanoprost lactone diolLatanoprost lactone diol is an intermediate in the synthesis of Latanoprost. Latanoprost is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP)[1]. |
| Name | (3aR,4R,5R,6aS)-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | Latanoprost lactone diol is an intermediate in the synthesis of Latanoprost. Latanoprost is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 523.0±35.0 °C at 760 mmHg |
| Melting Point | 69-71ºC |
| Molecular Formula | C18H24O4 |
| Molecular Weight | 304.381 |
| Flash Point | 190.3±19.4 °C |
| Exact Mass | 304.167450 |
| PSA | 66.76000 |
| LogP | 0.60 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.568 |
|
~79%
Latanoprost lac... CAS#:145667-75-0 |
| Literature: Chirogate International Inc. Patent: EP1810967 A1, 2007 ; Location in patent: Page/Page column 20-21 ; |
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~85%
Latanoprost lac... CAS#:145667-75-0 |
| Literature: Resul, Bahram; Stjernschantz, Johan; No, Kiyo; Liljebris, Charlotta; Selen, Goeran; et al. Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 243 - 248 |
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~%
Latanoprost lac... CAS#:145667-75-0 |
| Literature: EP1886992 A1, ; Page/Page column 9 ; |
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Latanoprost lac... CAS#:145667-75-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 36, # 2 p. 243 - 248 |
|
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Latanoprost lac... CAS#:145667-75-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 36, # 2 p. 243 - 248 |
|
~%
Latanoprost lac... CAS#:145667-75-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 36, # 2 p. 243 - 248 |
|
~%
Latanoprost lac... CAS#:145667-75-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 36, # 2 p. 243 - 248 |
|
~%
Latanoprost lac... CAS#:145667-75-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 36, # 2 p. 243 - 248 |
![(+)-(3Ar,4R,5R,6as)-hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-5-phenyl-1-pentenyl]-2H-cyclopenta[b]furan-2-one structure](https://image.chemsrc.com/caspic/387/41639-74-1.png)
![(3aR,4R,5R,6aS)-4-((R)-3-hydroxy-5-phenylpentyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate structure](https://image.chemsrc.com/caspic/009/353522-93-7.png)
![[1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-5-phenyl-1-pentenyl]-2H-cyclopenta[b]furan-5-yl ester structure](https://image.chemsrc.com/caspic/473/41639-72-9.png)
![(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-y l 4-biphenylcarboxylate structure](https://image.chemsrc.com/caspic/302/38754-71-1.png)
| (3aR,4R,5R,6aS)-5-Hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]hexahydro-2H-cyclopenta[b]furan-2-one |
| LatanoprostLactoneDiol |
| 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-, (3aR,4R,5R,6aS)- |