Tetomilast

Modify Date: 2024-01-05 21:03:21

Tetomilast Structure
Tetomilast structure
 Common Name Tetomilast
CAS Number 145739-56-6 Molecular Weight 369.434
Density 1.2±0.1 g/cm3 Boiling Point 526.1±50.0 °C at 760 mmHg
Molecular Formula C19H18N2O4S Melting Point N/A
MSDS N/A Flash Point 272.0±30.1 °C

 Use of Tetomilast


Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the treatment of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).

 Names

Name 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
Synonym More Synonyms

 Tetomilast Biological Activity

Description Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the treatment of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).
Related Catalog
References

[1]. Ichikawa H, Okamoto S, Kamada N, et al. Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice. Inflamm Bowel Dis. 2008;14(11):1483-1490.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 526.1±50.0 °C at 760 mmHg
Molecular Formula C19H18N2O4S
Molecular Weight 369.434
Flash Point 272.0±30.1 °C
Exact Mass 369.103485
PSA 109.78000
LogP 4.39
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.601

 Safety Information

HS Code 2934100090

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

Tetomilast
2-Pyridinecarboxylic acid, 6-[5-(3,4-diethoxyphenyl)-3-thienyl]-
UNII-S6RXB5KF56
6-[5-(3,4-Diethoxyphenyl)-3-thienyl]-2-pyridinecarboxylic acid
6-[2-(3,4-diethoxypheny)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
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Chemsrc provides Tetomilast(CAS#:145739-56-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Tetomilast are included as well.>> amp version: Tetomilast

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