PXS-4681A
Modify Date: 2024-01-13 20:52:50
PXS-4681A structure
|
Common Name | PXS-4681A | ||
|---|---|---|---|---|
| CAS Number | 1478364-87-2 | Molecular Weight | 296.741 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H14ClFN2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PXS-4681AA potent, selective, and irreversible inhibitor of SSAO/VAP-1 (AOC3) with Ki of 37 nM, IC50 of <10 nM; displays 250- and 4000-fold selectivity over DAO and LOX; attenuates neutrophil migration, TNF-α, and IL-6 levels in mouse models of lung inflammation and localized inflammation;orally activie. |
| Name | PXS-4681A |
|---|
| Description | A potent, selective, and irreversible inhibitor of SSAO/VAP-1 (AOC3) with Ki of 37 nM, IC50 of <10 nM; displays 250- and 4000-fold selectivity over DAO and LOX; attenuates neutrophil migration, TNF-α, and IL-6 levels in mouse models of lung inflammation and localized inflammation;orally activie. |
|---|---|
| References | References 1. Foot JS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):365-74. 2. Becchi S, et al. Br J Pharmacol. 2017 Jul;174(14):2302-2317. View Related Products by Target Other Targets |
| Molecular Formula | C10H14ClFN2O3S |
|---|---|
| Molecular Weight | 296.741 |