ABP 1 structure
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Common Name | ABP 1 | ||
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CAS Number | 1482293-92-4 | Molecular Weight | 384.367 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C13H16N6O6S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ABP 1A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro; covalently labels not only for canonical E1s (UBE1, SAE1/SAE2, NAE1/UBA3, UBE1L, and UBA6) but also for noncanonical E1s (UBA5 and ATG7). |
Name | ABP 1 |
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Description | A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro; covalently labels not only for canonical E1s (UBE1, SAE1/SAE2, NAE1/UBA3, UBE1L, and UBA6) but also for noncanonical E1s (UBA5 and ATG7). |
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References | References 1. An H, et al. J Am Chem Soc. 2013 Nov 13;135(45):16948-62. 2. An H, et al. Chem Sci. 2015 Sep 1;6(9):5235-5245. View Related Products by Target Ubiquitin-activating Enzyme (E1) |
Molecular Formula | C13H16N6O6S |
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Molecular Weight | 384.367 |