924298-51-1

924298-51-1 structure

Name: ABP 688
Chemical Name: (Z)-N-methoxy-3-[2-(6-methylpyridin-2-yl)ethynyl]cyclohex-2-en-1-imine
CAS Number: 924298-51-1
Molecular Formula: C₁₅H₁₆N₂O
Molecular Weight: 240.30000
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2017-07-08 22:45:19
Modify Date: 2024-01-11 20:52:58
ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].

Name	(Z)-N-methoxy-3-[2-(6-methylpyridin-2-yl)ethynyl]cyclohex-2-en-1-imine
Synonyms	abp688

Description	ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> mGluR
Target	human mGluR5:1.7 nM (Ki)
References	[1]. Hintermann S, et al. ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg Med Chem. 2007 Jan 15;15(2):903-14.