Hematoporphyrin monomethyl ether
Modify Date: 2024-01-03 23:29:17
Hematoporphyrin monomethyl ether structure
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Common Name | Hematoporphyrin monomethyl ether | ||
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| CAS Number | 148471-91-4 | Molecular Weight | 612.715 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1123.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C35H40N4O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 633.3±34.3 °C | |
Use of Hematoporphyrin monomethyl etherHematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma[1]. |
| Name | 3,3'-[7-(1-Hydroxyethyl)-12-(1-methoxyethyl)-3,8,13,17-tetramethy l-2,18-porphyrindiyl]dipropanoic acid |
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| Synonym | More Synonyms |
| Description | Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma[1]. |
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| Related Catalog | |
| In Vitro | Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT can induce cell deaththrough both necrosis and apoptosis in HeLa cells. ROS, such as singlet oxygen and hydroxyl radical, generated in HeLa cells play a decisive role in HMME-PDT-induced cell death[2]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1123.6±65.0 °C at 760 mmHg |
| Molecular Formula | C35H40N4O6 |
| Molecular Weight | 612.715 |
| Flash Point | 633.3±34.3 °C |
| Exact Mass | 612.294800 |
| PSA | 160.36000 |
| LogP | 6.87 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.622 |
| HeMatoporphyrinMonoMethylether |
| 21H,23H-Porphine-2,18-dipropanoic acid, 7-(1-hydroxyethyl)-12-(1-methoxyethyl)-3,8,13,17-tetramethyl- |
| 3,3'-[7-(1-Hydroxyethyl)-12-(1-methoxyethyl)-3,8,13,17-tetramethyl-2,18-porphyrindiyl]dipropanoic acid |
| Hematoporphyrinmonomethyl Ether |