Estrone sulfamate
Modify Date: 2024-01-09 16:50:22
Estrone sulfamate structure
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Common Name | Estrone sulfamate | ||
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| CAS Number | 148672-09-7 | Molecular Weight | 349.44500 | |
| Density | 1.314g/cm3 | Boiling Point | 530.9ºC at 760mmHg | |
| Molecular Formula | C18H23NO4S | Melting Point | 195-197ºC | |
| MSDS | USA | Flash Point | 274.9ºC | |
Use of Estrone sulfamateEstrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer[1]. |
| Name | [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfamate |
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| Synonym | More Synonyms |
| Description | Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer[1]. |
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| Related Catalog | |
| In Vitro | Estrone O-sulfamate (Estrone 3-O-sulfamate) 在胎盘微粒体 (P.M.) 制剂和 MCF-7 细胞中对 STS 具有抑制活性，IC50 值分别为 18 nM 和 0.83 nM[1]。 |
| References |
| Density | 1.314g/cm3 |
|---|---|
| Boiling Point | 530.9ºC at 760mmHg |
| Melting Point | 195-197ºC |
| Molecular Formula | C18H23NO4S |
| Molecular Weight | 349.44500 |
| Flash Point | 274.9ºC |
| Exact Mass | 349.13500 |
| PSA | 94.84000 |
| LogP | 4.47520 |
| Vapour Pressure | 2.35E-11mmHg at 25°C |
| Index of Refraction | 1.595 |
| Precursor 2 | |
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| DownStream 0 | |
CAS#:53-16-7
CAS#:1189-71-5| estrone sulfamate |
| Estra-1,3,5(10)-trien-17-one,3-((aminosulfonyl)oxy) |
| Emate compound |
| 3-sulfamoyloxyestra-1,3,5(10)-trien-17-one |
| Estra-1,3,5(10)-trien-17-one-3-sulfamate |
| Estrone-3-sulfamate |
| estrone-3-o-sulfamate |
| 3-((Aminosulfonyl)oxy)estra-1,3,5(10)-trien-17-one |
| Oestrone-3-O-sulphamate |
| 17-oxo-estra-1,3,5(10)-trien-3-yl sulfamate |
| EMATE |