Epigallocatechin gallate octaacetate

Modify Date: 2024-01-09 19:38:50

Epigallocatechin gallate octaacetate Structure
Epigallocatechin gallate octaacetate structure
Common Name Epigallocatechin gallate octaacetate
CAS Number 148707-39-5 Molecular Weight 794.66500
Density 1.46±0.1 g/cm3(Predicted) Boiling Point 879.7±65.0 °C(Predicted)
Molecular Formula C38H34O19 Melting Point 114.3-115.1 °C
MSDS N/A Flash Point N/A

 Use of Epigallocatechin gallate octaacetate


EGCG Octaacetate is a prodrug of Green tea epigallocatechin-3-gallate (EGCG), utilized to enhance the stability and bioavailability of EGCG in vivo. EGCG Octaacetate has high efficacy, bioavailability, anti-oxidation and anti-angiogenesis capacities[1]. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB) [2].

 Names

Name (-)-epigallocatechin 3-O-galloylperacetate
Synonym More Synonyms

 Epigallocatechin gallate octaacetate Biological Activity

Description EGCG Octaacetate is a prodrug of Green tea epigallocatechin-3-gallate (EGCG), utilized to enhance the stability and bioavailability of EGCG in vivo. EGCG Octaacetate has high efficacy, bioavailability, anti-oxidation and anti-angiogenesis capacities[1]. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB) [2].
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References

[1]. Wang CC, et al. Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice. Angiogenesis. 2013 Jan;16(1):59-69.

[2]. KalaiselviIgnasimuthu, et al. Enhanced bioaccessibility of green tea polyphenols and lipophilic activity of EGCG octaacetate on gram-negative bacteria. Volume 105, May 2019, Pages 103-109.

 Chemical & Physical Properties

Density 1.46±0.1 g/cm3(Predicted)
Boiling Point 879.7±65.0 °C(Predicted)
Melting Point 114.3-115.1 °C
Molecular Formula C38H34O19
Molecular Weight 794.66500
Exact Mass 794.16900
PSA 245.93000
LogP 3.99080

 Synonyms

(-)-Epigallocatechin gallate peracetate
(2R,3R)-5,7-bis(acetoxy)-2-[3',4',5'-tris(acetoxy)phenyl]chroman-3-yl 3,4,5-tris(acetoxy)benzoate
peracetyl EGCG
5-(((2R,3R)-5,7-diacetoxy-2-(3,4,5-triacetoxyphenyl)chroman-3-yloxy)carbonyl)benzene-1,2,3-triyl triacetate
3,4,5-Triacetoxy-benzoic acid (2R,3R)-5,7-diacetoxy-2-(3,4,5-triacetoxy-phenyl)-chroman-3-yl ester
EGCG peracetate
EGCG octaacetate
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