Poncirin

Modify Date: 2024-01-01 23:48:25

Poncirin Structure
Poncirin structure
Common Name Poncirin
CAS Number 14941-08-3 Molecular Weight 594.561
Density 1.6±0.1 g/cm3 Boiling Point 900.1±65.0 °C at 760 mmHg
Molecular Formula C28H34O14 Melting Point 210ºC
MSDS Chinese USA Flash Point 296.5±27.8 °C

 Use of Poncirin


Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models[1].

 Names

Name (2S)-poncirin
Synonym More Synonyms

 Poncirin Biological Activity

Description Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models[1].
Related Catalog
In Vivo Poncirin (intraperitoneal administration; 30 mg/kg) markedly reduces the pain behavior in both acetic acid-induced visceral pain and formalin-induced tonic pain models inComplete Freund’s Adjuvant (CFA)-induced inflammatory pain model[1].
References

[1]. Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog. 2009 Jun;48(6):498-507.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 900.1±65.0 °C at 760 mmHg
Melting Point 210ºC
Molecular Formula C28H34O14
Molecular Weight 594.561
Flash Point 296.5±27.8 °C
Exact Mass 594.194885
PSA 214.06000
LogP 3.39
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.678

 Safety Information

Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

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Poncirin Structure

Poncirin

CAS#:14941-08-3

Literature: Chen, Lao-Jer; Hrazdina, Geza Phytochemistry (Elsevier), 1981 , vol. 20, p. 297 - 304

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Poncirin Structure

Poncirin

CAS#:14941-08-3

Literature: Phytochemistry (Elsevier), , vol. 20, p. 297 - 304

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Poncirin Structure

Poncirin

CAS#:14941-08-3

Literature: Phytochemistry (Elsevier), , vol. 20, p. 297 - 304

 Synonyms

(2S)-7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one
Einecs 239-020-1
Neohesperidoside isosakuranetin-7
4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-, (2S)-
Poncirin
(2S)-5-Hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl-2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(2S)-7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxyméthyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}tétrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-méthoxyphényl)-2,3-dihydro-4H-chromén-4-one
Isosakuranetin 7-O-neohesperidoside
(S)-7-((2-O-(6-Deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one
ISOSAKURANETIN-7-NEOHESPERIDOSIDE
(2S)-7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-on
(S)-7-((2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one
4'-O-Methylnaringin
ISOSAKURANETIN-7-O-NEOHESPERIDOSID
(2S)-5-Hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
Isosakuranetin-7-O-neohesperidoside
Citrifolioside