Trovirdine

Modify Date: 2024-01-10 11:15:06

Trovirdine structure	Common Name	Trovirdine
	CAS Number	149488-17-5	Molecular Weight	337.23800
	Density	1.539g/cm3	Boiling Point	450.6ºC at 760mmHg
	Molecular Formula	C₁₃H₁₃BrN₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trovirdine

Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.IC50 value: 7 nMTarget: HIV-1Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.

Name	Trovirdine
Synonym	More Synonyms

Description	Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.IC50 value: 7 nMTarget: HIV-1Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127. [2]. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

References

[1]. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127.

[2]. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

Density	1.539g/cm3
Boiling Point	450.6ºC at 760mmHg
Molecular Formula	C₁₃H₁₃BrN₄S
Molecular Weight	337.23800
Exact Mass	336.00400
PSA	81.93000
LogP	3.23210
Appearance of Characters	light yellow solid
Vapour Pressure	2.61E-08mmHg at 25°C
Index of Refraction	1.696
Storage condition	-20℃

Thiourea,N-(5-bromo-2-pyridinyl)-N'-[2-(2-pyridinyl)ethyl]

Hi-142

LY-300046

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Trovirdine
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Trovirdine（LY300046）
Price: $500.0/100mg $900.0/250mg $1800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Trovirdine（LY300046）
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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Price: $312/10mM*1mLinDMSO

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Trovirdine

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