2-MPMDQ

Modify Date: 2024-03-07 13:24:44

2-MPMDQ structure	Common Name	2-MPMDQ
	CAS Number	149847-77-8	Molecular Weight	405.49
	Density	1.3±0.1 g/cm3	Boiling Point	578.2±60.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₇N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	303.5±32.9 °C

Use of 2-MPMDQ

2-MPMDQ is a potent and selective α1-adrenoceptor (Ki=0.37 nM) antagonist over α2-adrenoceptor (Ki=1740 nM). 2-MPMDQ is potent anti-hypertensive agent and has the potential for hypertension research[1].

Name	2-{[4-(2-Methoxyphenyl)-1-piperazinyl]methyl}-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one
Synonym	More Synonyms

Description	2-MPMDQ is a potent and selective α1-adrenoceptor (Ki=0.37 nM) antagonist over α2-adrenoceptor (Ki=1740 nM). 2-MPMDQ is potent anti-hypertensive agent and has the potential for hypertension research[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	α1-adrenergic receptor:0.37 nM (Ki) α2-adrenergic receptor:1740 nM (Ki)
References	[1]. J W Chern, et al. Studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. J Med Chem. 1993 Jul 23;36(15):2196-207.

Density	1.3±0.1 g/cm3
Boiling Point	578.2±60.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₇N₅O₂
Molecular Weight	405.49
Flash Point	303.5±32.9 °C
Exact Mass	405.216461
LogP	1.60
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.676

Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-

2-{[4-(2-Methoxyphenyl)-1-piperazinyl]methyl}-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one

2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-MPMDQ
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

2-MPMDQ suppliers

2-MPMDQ price

2-MPMDQ

Use of 2-MPMDQ

Names

2-MPMDQ Biological Activity

Chemical & Physical Properties

Synonyms