Ethylenediaminetetraacetic acid (trisodium salt)

Modify Date: 2024-01-02 16:36:31

Ethylenediaminetetraacetic acid (trisodium salt) Structure
Ethylenediaminetetraacetic acid (trisodium salt) structure
Common Name Ethylenediaminetetraacetic acid (trisodium salt)
CAS Number 150-38-9 Molecular Weight 358.19
Density N/A Boiling Point 614.2ºC at 760 mmHg
Molecular Formula C10H13N2Na3O8 Melting Point 237 °C
MSDS Chinese Flash Point 325.2ºC

 Use of Ethylenediaminetetraacetic acid (trisodium salt)


Ethylenediaminetetraacetic acid (EDTA) trisodium salt is used to bind metal ions in the practice of chelation therapy, for treating mercury and lead poisoning, used in a similar manner to remove excess iron from the body, for treating the complication of repeated blood transfusions, as would be applied to treat thalassaemia.

 Names

Name Ethylenediaminetetraacetic acid trisodium salt solution
Synonym More Synonyms

  Biological Activity

Description Ethylenediaminetetraacetic acid (EDTA) trisodium salt is used to bind metal ions in the practice of chelation therapy, for treating mercury and lead poisoning, used in a similar manner to remove excess iron from the body, for treating the complication of repeated blood transfusions, as would be applied to treat thalassaemia.
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 Chemical & Physical Properties

Boiling Point 614.2ºC at 760 mmHg
Melting Point 237 °C
Molecular Formula C10H13N2Na3O8
Molecular Weight 358.19
Flash Point 325.2ºC
PSA 182.63000
Vapour Pressure 1.15E-16mmHg at 25°C
Storage condition -20℃
Stability Stable. Incompatible with strong oxidizing agents, copper, aluminium.
Water Solubility H2O: clear, colorless to light yellow

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AH5250000
CHEMICAL NAME :
Acetic acid, (ethylenedinitrilo)tetra-, trisodium salt
CAS REGISTRY NUMBER :
150-38-9
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C10-H13-N2-O8.3Na
MOLECULAR WEIGHT :
358.22
WISWESSER LINE NOTATION :
QV1N1VO2N1VO1VO &-NA- 3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year: NCI-E-C-72-3252,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year: NCI-E-C-72-3252,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1- 1953- Volume(issue)/page/year: 10,391,1962 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82120 No. of Facilities: 2356 (estimated) No. of Industries: 19 No. of Occupations: 24 No. of Employees: 26820 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82120 No. of Facilities: 5994 (estimated) No. of Industries: 32 No. of Occupations: 34 No. of Employees: 50542 (estimated) No. of Female Employees: 14938 (estimated)

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25-S22
WGK Germany 3
RTECS AH5250000
HS Code 29173990

 Synonyms

tetrasodium edetate
tetrasodium ethylenediaminetetraacetate
EDTA disodium salt
EDTA 3NA
EDTA.Na3
EDTA tetrasodium salt
acetate, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, hydrogen sodium salt (1:1:3)
edetate tetrasodium
MFCD00149675
Sequestrene NA 3
Edetic Acid Trisodium Salt
Trisodium 2,2'-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}imino)diacetate
edta trisodium
N,N'-1,2-Ethanediylbis[N-(carboxymethyl)glycine] Trisodium Salt
Trisodium ethylenediaminetetraacetate dihydrate
Sodium hydrogen 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate (3:1:1)
EINECS 205-758-8
trisodiumedta
Ethylenediaminetetraacetic acid (trisodium salt)
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