Ledipasvir diacetone

Modify Date: 2024-01-07 08:47:04

Ledipasvir diacetone Structure
Ledipasvir diacetone structure
Common Name Ledipasvir diacetone
CAS Number 1502655-48-2 Molecular Weight 1005.16000
Density N/A Boiling Point N/A
Molecular Formula C55H66F2N8O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ledipasvir diacetone


Ledipasvir diacetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.

 Names

Name Ledipasvir diacetone
Synonym More Synonyms

 Ledipasvir diacetone Biological Activity

Description Ledipasvir diacetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
Related Catalog
In Vitro Ledipasvir diacetone is considered the active pharmaceutical ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base.

 Chemical & Physical Properties

Molecular Formula C55H66F2N8O8
Molecular Weight 1005.16000
Exact Mass 1004.50000
PSA 208.78000
LogP 10.45550
Storage condition 2-8℃

 Synonyms

Methyl N-[(2S)-1-[(6S)-6-[5-[9,9-Difluoro-7-[2-[(1S,2S,4R)-3-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate diacetone
GS-5885 diacetone
methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate compound with propan-2-one (1:2)
Ledipasvir (diacetone)
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