PD 134922

Modify Date: 2024-03-26 16:14:03

PD 134922 structure	Common Name	PD 134922
	CAS Number	150351-30-7	Molecular Weight	719.97500
	Density	1.19g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₇H₆₁N₅O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PD 134922

PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].

Name	(2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]pent-4-enoyl]amino]-2-propan-2-ylhexanamide

Description	PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease Signaling Pathways >> Metabolic Enzyme/Protease >> Renin
Target	IC50: 15 nM (HIV-1 protease)[1]
References	[1]. Humblet CC, et al. Characterization of two structurally novel HIV-1 protease inhibitors identified by rational selection. Antiviral Res. 1993 May;21(1):73-84.

Density	1.19g/cm3
Molecular Formula	C₃₇H₆₁N₅O₇S
Molecular Weight	719.97500
Exact Mass	719.42900
PSA	185.02000
LogP	7.15040
Index of Refraction	1.565