QO IIR

Modify Date: 2024-01-19 11:52:43

QO IIR Structure
QO IIR structure
Common Name QO IIR
CAS Number 150404-10-7 Molecular Weight 285.25
Density N/A Boiling Point N/A
Molecular Formula C15H11NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of QO IIR


QO IIR is a reversible, tight-binding inhibitor inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 320 nM; fully reverses the reserpine-induced catalepsy in vivo, demonstrates behavioural and neurochemical effects in reserpinized rats treated with LD/CD.

 Names

Name QO IIR
Synonym More Synonyms

 QO IIR Biological Activity

Description QO IIR is a reversible, tight-binding inhibitor inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 320 nM; fully reverses the reserpine-induced catalepsy in vivo, demonstrates behavioural and neurochemical effects in reserpinized rats treated with LD/CD.
References References 1. Rivas E, et al. Br J Pharmacol. 1999 Apr;126(7):1667-73. 2. Pérez RA, et al. Biochem Pharmacol. 1993 May 25;45(10):1973-81. View Related Products by Target COMT

 Chemical & Physical Properties

Molecular Formula C15H11NO5
Molecular Weight 285.25
Exact Mass 285.063722

 Synonyms

(E)-3-(3,4-Dihydroxy-2-nitrophenyl)-1-phenylprop-2-en-1-one
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