Cyclophilin inhibitor 1

Modify Date: 2024-01-09 12:24:47

Cyclophilin inhibitor 1 Structure
Cyclophilin inhibitor 1 structure
Common Name Cyclophilin inhibitor 1
CAS Number 1509904-96-4 Molecular Weight 593.67
Density N/A Boiling Point N/A
Molecular Formula C31H39N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cyclophilin inhibitor 1


Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].

 Names

Name Cyclophilin inhibitor 1

 Cyclophilin inhibitor 1 Biological Activity

Description Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].
Related Catalog
Target

Kd: 5 nM (Cyclophilin A)[1] EC50: 98 nM (HCV 2a)[1]

In Vitro Cyclophilin inhibitor 1 (Compound 3) inhibits HCV 2a activity, with an EC50 of 98 nM[1].
References

[1]. Mackman RL, et al. Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. J Med Chem. 2018 Nov 8;61(21):9473-9499.

 Chemical & Physical Properties

Molecular Formula C31H39N5O7
Molecular Weight 593.67