6α-Hydroxy paclitaxel

Modify Date: 2024-01-04 18:57:28

6α-Hydroxy paclitaxel structure	Common Name	6α-Hydroxy paclitaxel
	CAS Number	153212-75-0	Molecular Weight	869.906
	Density	1.4±0.1 g/cm3	Boiling Point	979.8±65.0 °C at 760 mmHg
	Molecular Formula	C₄₇H₅₁NO₁₅	Melting Point	177-180ºC
	MSDS	N/A	Flash Point	546.4±34.3 °C

Use of 6α-Hydroxy paclitaxel

6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion–transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer[1].

Name	6-hydroxypaclitaxel
Synonym	More Synonyms

Description	6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion–transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Mori D, et al. Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel. Drug Metab Dispos. 2020 May;48(5):387-394.

Density	1.4±0.1 g/cm3
Boiling Point	979.8±65.0 °C at 760 mmHg
Melting Point	177-180ºC
Molecular Formula	C₄₇H₅₁NO₁₅
Molecular Weight	869.906
Flash Point	546.4±34.3 °C
Exact Mass	869.325867
PSA	241.52000
LogP	7.32
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.646
Storage condition	2-8°C

Hazard Codes	Xn

(2α,3ξ,5β,6α,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,6,7-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate

6α-Hydroxy Paclitaxel

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,3S,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-3,4,11-trihydroxy-4 a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,3S,4R,4aS,6R,9S,11S,12S,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-3,4,11-trihydroxy-4a,8,1 3,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

6-Hydroxytaxol

6-hydroxypaclitaxel

DC Chemicals Limited
China
Product Name: 6α-Hydroxy paclitaxel
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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