Gavestinel

Modify Date: 2024-01-17 10:44:13

Gavestinel structure	Common Name	Gavestinel
	CAS Number	153436-22-7	Molecular Weight	375.21
	Density	1.561g/cm3	Boiling Point	701.1ºC at 760mmHg
	Molecular Formula	C₁₈H₁₂Cl₂N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	377.8ºC

Use of Gavestinel

Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].

Name	3-[(E)-3-anilino-3-oxoprop-1-enyl]-4,6-dichloro-1H-indole-2-carboxylic acid
Synonym	More Synonyms

Description	Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. J F Hoke, et al. Pharmacokinetics of a glycine site antagonist (gavestinel) following multiple dosing in patients with acute stroke. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):867-72.

Density	1.561g/cm3
Boiling Point	701.1ºC at 760mmHg
Molecular Formula	C₁₈H₁₂Cl₂N₂O₃
Molecular Weight	375.21
Flash Point	377.8ºC
Exact Mass	396.00400
PSA	85.02000
LogP	3.56310
Vapour Pressure	1.24E-20mmHg at 25°C

Gavestinel