2'-C-Methyladenosine
Modify Date: 2024-01-11 00:38:03
2'-C-Methyladenosine structure
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Common Name | 2'-C-Methyladenosine | ||
|---|---|---|---|---|
| CAS Number | 15397-12-3 | Molecular Weight | 281.268 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 643.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C11H15N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 342.9±34.3 °C | |
Use of 2'-C-Methyladenosine2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication. 2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC50 values of 0.3μM and 1.9 μM, respectively. 2'-C-Methyladenosine also potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis[1][2]. |
| Name | (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol |
|---|---|
| Synonym | More Synonyms |
| Description | 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication. 2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC50 values of 0.3μM and 1.9 μM, respectively. 2'-C-Methyladenosine also potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis[1][2]. |
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| Related Catalog | |
| Target |
IC50: 0.3μM (HCV replicon); 1.9 μM (NS5B)[1] |
| In Vivo | 2'-C-Methyladenosine has inhibitory potency for HCV replicon in HB110A cells with an IC50 values of 0.3μM[1]. 2'-C-Methyladenosine inhibits NS5B-catalyzed RNA synthesis with an IC50 values of 1.9 μM[1]. 2′-C-methyladenosine potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis[2] |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 643.4±65.0 °C at 760 mmHg |
| Molecular Formula | C11H15N5O4 |
| Molecular Weight | 281.268 |
| Flash Point | 342.9±34.3 °C |
| Exact Mass | 281.112396 |
| PSA | 139.54000 |
| LogP | 0.55 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.823 |
| 2'-C-Methyladenosine |
| 2-(6-amino-purin-9-yl)-5-hydroxymethyl-3-methyl-tetrahydrofuran-3,4-diol |
| 2'-METHYLADENOSINE |
| 2'-C-methyl adenosine |
| Adenosine, 2'-C-methyl- |