19-Hydroxy-10-deacetylbaccatin III

Modify Date: 2024-04-08 23:06:26

19-Hydroxy-10-deacetylbaccatin III Structure
19-Hydroxy-10-deacetylbaccatin III structure
Common Name 19-Hydroxy-10-deacetylbaccatin III
CAS Number 154083-99-5 Molecular Weight 560.59
Density N/A Boiling Point N/A
Molecular Formula C29H36O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 19-Hydroxy-10-deacetylbaccatin III


19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].

 Names

Name Cabazitaxel Impurity 30
Synonym More Synonyms

 19-Hydroxy-10-deacetylbaccatin III Biological Activity

Description 19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].
Related Catalog
References

[1]. Shen YC, et al. Three new taxane diterpenoids from Taxus sumatrana. J Nat Prod. 2005 Jan;68(1):90-3.  

 Chemical & Physical Properties

Molecular Formula C29H36O11
Molecular Weight 560.59

 Synonyms

19-羟基-10-脱乙酰基巴卡亭III