PBB3

Modify Date: 2023-01-17 12:54:09

PBB3 structure	Common Name	PBB3
	CAS Number	1565796-97-5	Molecular Weight	309.39
	Density	1.4±0.1 g/cm3	Boiling Point	572.4±60.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₅N₃OS	Melting Point	N/A
	MSDS	N/A	Flash Point	300.0±32.9 °C

Use of PBB3

PBB3, a selective PET ligand, recognizes tau pathology in Alzheimer's disease brains, where dystrophic neurites and diffuse neurofibrils are more clearly detected Tangles with calcification[1].

Name	6-Benzothiazolol, 2-[(1E,3E)-4-[6-(methylamino)-3-pyridinyl]-1,3-butadien-1-yl]-
Synonym	More Synonyms

Description	PBB3, a selective PET ligand, recognizes tau pathology in Alzheimer's disease brains, where dystrophic neurites and diffuse neurofibrils are more clearly detected Tangles with calcification[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Maiko Ono, et al. Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies. Brain. 2017 Mar 1;140(3):764-780.

Density	1.4±0.1 g/cm3
Boiling Point	572.4±60.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₅N₃OS
Molecular Weight	309.39
Flash Point	300.0±32.9 °C
Exact Mass	309.093567
LogP	3.30
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.797

PBB-3

2-{(1E,3E)-4-[6-(Methylamino)-3-pyridinyl]-1,3-butadien-1-yl}-1,3-benzothiazol-6-ol

6-Benzothiazolol, 2-[(1E,3E)-4-[6-(methylamino)-3-pyridinyl]-1,3-butadien-1-yl]-

PBB3

Use of PBB3

Names

PBB3 Biological Activity

Chemical & Physical Properties

Synonyms