3-Pyridinecarboxylicacid, 6,6'-dithiobis-

Modify Date: 2024-01-10 00:05:07

3-Pyridinecarboxylicacid, 6,6'-dithiobis- structure	Common Name	3-Pyridinecarboxylicacid, 6,6'-dithiobis-
	CAS Number	15658-35-2	Molecular Weight	308.33
	Density	1.66g/cm3	Boiling Point	584.2ºC at 760mmHg
	Molecular Formula	C₁₂H₈N₂O₄S₂	Melting Point	263-265 °C(lit.)
	MSDS	Chinese USA	Flash Point	307.1ºC
	Symbol	GHS07	Signal Word	Warning

Use of 3-Pyridinecarboxylicacid, 6,6'-dithiobis-

6,6′-Dithiodinicotinic acid is a sulfur-containing organic compound belonging to nicotinic acid derivatives, which can be used as a specific sulfhydryl blocker[1].

Name	6,6'-dithiodinicotinic acid
Synonym	More Synonyms

Description	6,6′-Dithiodinicotinic acid is a sulfur-containing organic compound belonging to nicotinic acid derivatives, which can be used as a specific sulfhydryl blocker[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Samir Abou-Khalil, et al. Effects of 6,6′-dithiodinicotinic acid, a thiol reagent on several mitochondrial functions: Coupling mechanism, ATPase and anion transport.Biochemical Pharmacology.Volume 24, Issue 1, 1 January 1975, Pages 49-56.

Density	1.66g/cm3
Boiling Point	584.2ºC at 760mmHg
Melting Point	263-265 °C(lit.)
Molecular Formula	C₁₂H₈N₂O₄S₂
Molecular Weight	308.33
Flash Point	307.1ºC
Exact Mass	307.99300
PSA	150.98000
LogP	2.67240
Vapour Pressure	1.71E-14mmHg at 25°C
Index of Refraction	1.753
Stability	Stable. Incompatible with strong oxidizing agents.

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US5684700

CHEMICAL NAME :: 3-Pyridinecarboxylic acid, 6,6'-dithiobis-

CAS REGISTRY NUMBER :: 15658-35-2

BEILSTEIN REFERENCE NO. :: 0426589

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H8-N2-O4-S2

MOLECULAR WEIGHT :: 308.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,559,1986

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	US5684700
HS Code	2933399090

Precursor 0
DownStream 2
CAS#:17624-07-6 3-Pyridinecarbo... CAS#:74470-34-1 methyl 6-sulfan...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Effects of 6,6'-dithiodinicotinic acid (CPDS) and its metabolite 6-mercaptonicotinic acid (6-MNA) on murine and hamster fibroblasts (3T3 and BHK) and murine metastatic melanoma cells (F10).

Chemioterapia 5(4) , 219-27, (1986)

We investigated the action of 6,6'-dithiodinicotinic acid (CPDS) and its metabolite 6-mercaptonicotinic acid (6-MNA) in vitro on murine (3T3) and baby hamster kidney (BHK) fibroblasts and an in vivo h...

Assay of biological thiols by a combination of high-performance liquid chromatography and postcolumn reaction with 6,6'-dithiodinicotinic acid.

Anal. Biochem. 138(1) , 95-8, (1984)

A simple and rapid method for the determination of nanomole levels of biological thiols is described. The analysis is based on the combination of reverse-phase high-performance liquid chromatography w...

Role of membrane-associated thiol groups in the functional regulation of gastric microsomal (H+ + K+)-transporting ATPase system.

Biochem. J. 213(3) , 587-94, (1983)

The distribution of free thiol groups associated with the membrane proteins of the purified pig gastric microsomal vesicles was quantified, and the relation of thiol groups to the function of the gast...

MFCD00006454

6,6'-Dithiobis(3-pyridinecarboxylic Acid)

EINECS 239-729-6

6,6'-Dithiodinicotinic Acid

6-[(5-carboxypyridin-2-yl)disulfanyl]pyridine-3-carboxylic acid