Org 20599

Modify Date: 2024-03-03 10:57:15

Org 20599 Structure
Org 20599 structure
Common Name Org 20599
CAS Number 156685-94-8 Molecular Weight 438.04300
Density N/A Boiling Point N/A
Molecular Formula C25H40ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Org 20599


Org20599 is a positive allosteric modulator and at higher concentrations direct agonist of GABAA receptor with an EC50 of 1.1 μM[1].

 Names

Name 2-chloro-1-[(2S,3S,5S,10S,13S)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Synonym More Synonyms

 Org 20599 Biological Activity

Description Org20599 is a positive allosteric modulator and at higher concentrations direct agonist of GABAA receptor with an EC50 of 1.1 μM[1].
Related Catalog
References

[1]. Visser SA, et al. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303(2):616-26.

 Chemical & Physical Properties

Molecular Formula C25H40ClNO3
Molecular Weight 438.04300
Exact Mass 437.27000
PSA 49.77000
LogP 4.06270

 Synonyms

YS-035 hydrochloride
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