Teneligliptin hydrobromide hydrate

Modify Date: 2024-01-08 11:33:43

Teneligliptin hydrobromide hydrate Structure
Teneligliptin hydrobromide hydrate structure
Common Name Teneligliptin hydrobromide hydrate
CAS Number 1572583-29-9 Molecular Weight 1275.731
Density N/A Boiling Point N/A
Molecular Formula C22H30N6OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Teneligliptin hydrobromide hydrate


Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].

 Names

Name Teneligliptin sesquihydrobromide hydrate
Synonym More Synonyms

 Teneligliptin hydrobromide hydrate Biological Activity

Description Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].
Related Catalog
References

[1]. Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.

 Chemical & Physical Properties

Molecular Formula C22H30N6OS
Molecular Weight 1275.731
Exact Mass 1270.081665
Storage condition 2-8℃

 Synonyms

Teneligliptin sesquihydrobromide hydrate
Methanone, [(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-, hydrobromide, hydrate (2:5:1)
{(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl}(1,3-thiazolidin-3-yl)methanone hydrobromide hydrate (2:5:1)
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Price: ¥600/10 mg

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