1-Ethynylnaphthalene

Modify Date: 2024-01-02 11:50:49

1-Ethynylnaphthalene structure	Common Name	1-Ethynylnaphthalene
	CAS Number	15727-65-8	Molecular Weight	152.19200
	Density	1.070 g/mL at 25ºC(lit.)	Boiling Point	270.4ºC at 760 mmHg
	Molecular Formula	C₁₂H₈	Melting Point	N/A
	MSDS	N/A	Flash Point	106.3ºC

Use of 1-Ethynylnaphthalene

1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1.

Name	1-ethynylnaphthalene
Synonym	More Synonyms

Description	1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Cancer
Target	P450 1B1[1]
In Vitro	1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%[1].
References	[1]. Liehr JG, et al. 4-Hydroxylation of estradiol by human uterine myometrium and myoma microsomes: implications for the mechanism of uterine tumorigenesis. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9220-4.

Density	1.070 g/mL at 25ºC(lit.)
Boiling Point	270.4ºC at 760 mmHg
Molecular Formula	C₁₂H₈
Molecular Weight	152.19200
Flash Point	106.3ºC
Exact Mass	152.06300
LogP	2.82110
Vapour Pressure	0.0114mmHg at 25°C
Index of Refraction	n20/D 1.6500(lit.)
Storage condition	2-8℃

Risk Phrases	R10
Safety Phrases	16
RIDADR	UN 1993 3
HS Code	2902909090

Precursor 10
CAS#:40888-18-4 2-methyl-4-naph... CAS#:104784-51-2 1-(1-Naphthyl)-... CAS#:90-14-2 1-Iodonaphthalene CAS#:471-25-0 Propiolic acidd
CAS#:1066-54-2 TMS-acetylene CAS#:66-77-3 naphthal CAS#:90965-06-3 Dimethyl (1-dia... CAS#:4843-42-9 3-naphthalen-1-...
CAS#:90-11-9 1-Bromonaphthalene CAS#:85924-92-1 1-methylene-1H-...
DownStream 10
CAS#:941-98-0 1'-Acetonaphthone CAS#:104784-51-2 1-(1-Naphthyl)-... CAS#:604-53-5 binaphthyl CAS#:32137-38-5 1-prop-1-ynylna...
CAS#:16176-22-0 3-(1-NAPHTHYL)-... CAS#:233-02-3 naphtho[2,1-b]t... CAS#:217-37-8 Benzo[c]picene CAS#:1044536-18-6 1,2,4-tris-(1'-...
CAS#:21532-73-0 1-(1'-naphthyl)... CAS#:7059-70-3 1,3,5-Tri(1-nap...

HS Code	2902909090
Summary	2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

1-(ethynyl)naphthalene

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MFCD02093737

ethynyl-naphthalene

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-Ethynylnaphthalene
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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Price: $50/100mg

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