Taxuspine B
Modify Date: 2024-01-15 13:44:02
Taxuspine B structure
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Common Name | Taxuspine B | ||
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| CAS Number | 157414-05-6 | Molecular Weight | 622.70 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 709.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C35H42O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 216.8±26.4 °C | |
Use of Taxuspine BTaxuspine B is a natural product, that can be isolated from Japanese yew Taxus. Taxuspine B exhibits appreciable taxol-like activity to reduce CaCl2-induced depolymerixation of microtubules among the taxoids[1]. |
| Name | (1R,2S,3E,5S,7S,8S,10R,13S)-2,7,13-Triacetoxy-10-hydroxy-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.14,8]hexadeca-3,11-dien-5-yl (2E)-3-phenylacrylate |
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| Synonym | More Synonyms |
| Description | Taxuspine B is a natural product, that can be isolated from Japanese yew Taxus. Taxuspine B exhibits appreciable taxol-like activity to reduce CaCl2-induced depolymerixation of microtubules among the taxoids[1]. |
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| Related Catalog | |
| In Vitro | Taxuspine B 对小鼠淋巴瘤 L1210 (IC50=18 μg/mL) 和人表皮样癌 KB 细胞表现出较弱的细胞毒性，在 10 μg/mL 时抑制率分别为 42.3% 和 11.8% [1]。 |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 709.1±60.0 °C at 760 mmHg |
| Molecular Formula | C35H42O10 |
| Molecular Weight | 622.70 |
| Flash Point | 216.8±26.4 °C |
| Exact Mass | 622.277771 |
| LogP | 5.14 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.573 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
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| (1R,2S,3E,5S,7S,8S,10R,13S)-2,7,13-Triacetoxy-10-hydroxy-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.14,8]hexadeca-3,11-dien-5-yl (2E)-3-phenylacrylate |
| 2-Propenoic acid, 3-phenyl-, (1R,2S,3E,5S,7S,8S,10R,13S)-2,7,13-tris(acetyloxy)-10-hydroxy-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.14,8]hexadeca-3,11-dien-5-yl ester, (2E)- |
| (1R,2S,3E,5S,7S,8S,10R,13S)-2,7,13-tris(acetyloxy)-10-hydroxy-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.14,8]hexadeca-3,11-dien-5-yl (2E)-3-phenylprop-2-enoate |