Diroximel fumarate

Modify Date: 2024-01-08 21:37:31

Diroximel fumarate Structure
Diroximel fumarate structure
Common Name Diroximel fumarate
CAS Number 1577222-14-0 Molecular Weight 255.224
Density 1.3±0.1 g/cm3 Boiling Point 441.0±25.0 °C at 760 mmHg
Molecular Formula C11H13NO6 Melting Point N/A
MSDS N/A Flash Point 220.5±23.2 °C

 Use of Diroximel fumarate


Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1].

 Names

Name Diroxamel fumarate
Synonym More Synonyms

 Diroximel fumarate Biological Activity

Description Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1].
Related Catalog
References

[1]. Angela Wehr, et al. Relative Bioavailability of Monomethyl Fumarate after Administration of ALKS 8700 and Dimethyl Fumarate in Healthy Subjects (P1.403). Neurology. Apr 2018.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 441.0±25.0 °C at 760 mmHg
Molecular Formula C11H13NO6
Molecular Weight 255.224
Flash Point 220.5±23.2 °C
Exact Mass 255.074280
LogP -0.24
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.515
Storage condition -20℃

 Synonyms

ALKS 8700
2-Butenedioic acid, 2-(2,5-dioxo-1-pyrrolidinyl)ethyl methyl ester, (2E)-
MFCD28502263
2-(2,5-Dioxo-1-pyrrolidinyl)ethyl methyl (2E)-2-butenedioate
Diroxamel fumarate
Diroximel fumarate
RDC-5108
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Price: ¥1650/10 mM * 1 mL in DMSO

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