BMS-986115

Modify Date: 2024-01-06 19:58:06

BMS-986115 Structure
BMS-986115 structure
Common Name BMS-986115
CAS Number 1584647-27-7 Molecular Weight 574.49
Density N/A Boiling Point N/A
Molecular Formula C26H25F7N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-986115


Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].

 Names

Name Notch inhibitor 1

 BMS-986115 Biological Activity

Description Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].
Related Catalog
Target

IC50: 7.8 nM (Notch 1), 8.5 nM (Notch 3)[1]

In Vitro Notch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway[1].
References

[1]. Ashvinikumar V. Gavai, et al. Bis(fluoroalkyl)-1,4-benzodiazepinone compounds as notch inhibitors. WO2014047372A1.

 Chemical & Physical Properties

Molecular Formula C26H25F7N4O3
Molecular Weight 574.49
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