Frovatriptan

Modify Date: 2024-01-17 10:30:35

Frovatriptan Structure
Frovatriptan structure
Common Name Frovatriptan
CAS Number 158747-02-5 Molecular Weight 243.30
Density 1.27g/cm3 Boiling Point 515.2ºC at 760mmHg
Molecular Formula C14H17N3O Melting Point N/A
MSDS N/A Flash Point 265.4ºC

 Use of Frovatriptan


Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[1].

 Names

Name (6R)-6-(methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide
Synonym More Synonyms

 Frovatriptan Biological Activity

Description Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[1].
Related Catalog
References

[1]. Stefan Evers, et al. Efficacy of frovatriptan as compared to other triptans in migraine with aura.

 Chemical & Physical Properties

Density 1.27g/cm3
Boiling Point 515.2ºC at 760mmHg
Molecular Formula C14H17N3O
Molecular Weight 243.30
Flash Point 265.4ºC
Exact Mass 243.13700
PSA 71.90000
LogP 2.61860
Vapour Pressure 1.01E-10mmHg at 25°C
Index of Refraction 1.667

 Synonyms

Frovatriptan (INN)
Auradol
Frova
Frovelan
Miguard
Rilamig
UNII-H82Q2D5WA7
Migard
Allegro