MC-Val-Cit-PAB-OH
Modify Date: 2024-01-03 14:40:58
MC-Val-Cit-PAB-OH structure
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Common Name | MC-Val-Cit-PAB-OH | ||
|---|---|---|---|---|
| CAS Number | 159857-80-4 | Molecular Weight | 572.65300 | |
| Density | 1.276 | Boiling Point | N/A | |
| Molecular Formula | C28H40N6O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MC-Val-Cit-PAB-OHMC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker. |
| Name | N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N5-carbamoyl-N2-[4-(hydroxymethyl)phenyl]-L-ornithinamide |
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| Synonym | More Synonyms |
| Description | MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker. |
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| Related Catalog | |
| Target |
ADC linker[1] |
| References |
[1]. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders |
| Density | 1.276 |
|---|---|
| Molecular Formula | C28H40N6O7 |
| Molecular Weight | 572.65300 |
| Exact Mass | 572.29600 |
| PSA | 210.70000 |
| LogP | 3.27310 |
| Storage condition | 2-8℃ |
|
~94%
MC-Val-Cit-PAB-OH CAS#:159857-80-4 |
| Literature: SEATTLE GENETICS, INC. Patent: WO2007/8848 A2, 2007 ; Location in patent: Page/Page column 108; 136; 137 ; |
| MC-Val-Cit-PAB |