(S)-16-Amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic acid

Modify Date: 2024-01-13 22:27:37

(S)-16-Amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic acid Structure
(S)-16-Amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic acid structure
Common Name (S)-16-Amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic acid
CAS Number 1599440-20-6 Molecular Weight 423.42
Density 1.339±0.06 g/cm3(Predicted) Boiling Point 971.9±65.0 °C(Predicted)
Molecular Formula C18H25N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-16-Amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic acid


Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].

 Names

Name Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]-

  Biological Activity

Description Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].
Related Catalog
References

[1]. Masuda,et al. Preparation of antibody-drug conjugates for cancer therapy. World Intellectual Property Organization, WO2014057687 A1. 2014-04-17.

 Chemical & Physical Properties

Density 1.339±0.06 g/cm3(Predicted)
Boiling Point 971.9±65.0 °C(Predicted)
Molecular Formula C18H25N5O7
Molecular Weight 423.42