β-N-methylamino-L-alanine hydrochloride

Modify Date: 2024-01-01 18:22:00

β-N-methylamino-L-alanine hydrochloride structure	Common Name	β-N-methylamino-L-alanine hydrochloride
	CAS Number	16012-55-8	Molecular Weight	154.595
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄H₁₁ClN₂O₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of β-N-methylamino-L-alanine hydrochloride

β-N-methylamino-L-alanine hydrochloride (BMAA hydrochloride) is a neurotoxin produced by cyanobacteria, could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases[1][2][3].

Name	S(+)-2-Amino-3-(methylamino)propionic acid hydrochloride
Synonym	More Synonyms

Description	β-N-methylamino-L-alanine hydrochloride (BMAA hydrochloride) is a neurotoxin produced by cyanobacteria, could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Caller T, et, al. The Potential Role of BMAA in Neurodegeneration. Neurotox Res. 2018 Jan; 33(1): 222-226. [2]. Cox PA, et, al. BMAA and Neurodegenerative Illness. Neurotox Res. 2018 Jan; 33(1): 178-183. [3]. Okamoto S, et, al. β-N-methylamino-L-alanine (BMAA) suppresses cell cycle progression of non-neuronal cells. Sci Rep. 2018 Dec 20; 8(1): 17995.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Caller T, et, al. The Potential Role of BMAA in Neurodegeneration. Neurotox Res. 2018 Jan; 33(1): 222-226.

[2]. Cox PA, et, al. BMAA and Neurodegenerative Illness. Neurotox Res. 2018 Jan; 33(1): 178-183.

[3]. Okamoto S, et, al. β-N-methylamino-L-alanine (BMAA) suppresses cell cycle progression of non-neuronal cells. Sci Rep. 2018 Dec 20; 8(1): 17995.

Molecular Formula	C₄H₁₁ClN₂O₂
Molecular Weight	154.595
Exact Mass	154.050903
PSA	75.35000
LogP	0.51090
Storage condition	-20°C

β-N-methylamino-L-alanine hydrochloride MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H332-H315-H319
Precautionary Statements	P261-P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
HS Code	2922499990

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Improving derivatization efficiency of BMAA utilizing AccQ-Tag in a complex cyanobacterial matrix.

Amino Acids 36 , 43-8, (2009)

Two different assays have been developed and used in order to investigate the optimal conditions for derivatization and detection of acid beta-N-methyl-amino-L-alanine (BMAA) in a cyanobacterial sampl...

Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin.

Science 237 , 517, (1987)

The decline in the high incidence of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer-type dementia among the Chamorro population of the western Pacific islands of Guam and Rota, coupled wit...

Beta-N-methylamino-L-alanine (L-BMAA) is a potent agonist of 'metabolotropic' glutamate receptors.

Eur. J. Pharmacol. 181 , 327-328, (1990)