Osanetant
Modify Date: 2024-01-13 16:49:22
Osanetant structure
|
Common Name | Osanetant | ||
|---|---|---|---|---|
| CAS Number | 160492-56-8 | Molecular Weight | 606.62500 | |
| Density | 1.25g/cm3 | Boiling Point | 727.9ºC at 760mmHg | |
| Molecular Formula | C35H41Cl2N3O2 | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | 394ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of OsanetantOsanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for the treatment of schizophrenia[1]. |
| Name | N-(1-{3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]prop yl}-4-phenyl-4-piperidinyl)-N-methylacetamide |
|---|
| Description | Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for the treatment of schizophrenia[1]. |
|---|---|
| Related Catalog | |
| Target |
NK3 |
| In Vivo | Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time[1]. Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time[1]. Animal Model: Male Mongolian gerbils of 7 weeks old (50-60 g)[1] Dosage: 1, 3 and 10 mg/kg Administration: Po; 60 min before testing Result: Significantly increased social interaction time. |
| References |
| Density | 1.25g/cm3 |
|---|---|
| Boiling Point | 727.9ºC at 760mmHg |
| Molecular Formula | C35H41Cl2N3O2 |
| Molecular Weight | 606.62500 |
| Flash Point | 394ºC |
| Exact Mass | 605.25800 |
| PSA | 43.86000 |
| LogP | 7.29300 |
| Vapour Pressure | 4.79E-21mmHg at 25°C |
| Index of Refraction | 1.633 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |