Osanetant

Modify Date: 2024-01-13 16:49:22

Osanetant structure	Common Name	Osanetant
	CAS Number	160492-56-8	Molecular Weight	606.62500
	Density	1.25g/cm3	Boiling Point	727.9ºC at 760mmHg
	Molecular Formula	C₃₅H₄₁Cl₂N₃O₂	Melting Point	N/A
	MSDS	Chinese	Flash Point	394ºC
	Symbol	GHS07	Signal Word	Warning

Use of Osanetant

Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for the treatment of schizophrenia[1].

Name	N-(1-{3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]prop yl}-4-phenyl-4-piperidinyl)-N-methylacetamide

Description	Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for the treatment of schizophrenia[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Target	NK3
In Vivo	Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time[1]. Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time[1]. Animal Model: Male Mongolian gerbils of 7 weeks old (50-60 g)[1] Dosage: 1, 3 and 10 mg/kg Administration: Po; 60 min before testing Result: Significantly increased social interaction time.
References	[1]. Salomé N, et al. Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. Pharmacol Biochem Behav. 2006 Apr;83(4):533-9.

Density	1.25g/cm3
Boiling Point	727.9ºC at 760mmHg
Molecular Formula	C₃₅H₄₁Cl₂N₃O₂
Molecular Weight	606.62500
Flash Point	394ºC
Exact Mass	605.25800
PSA	43.86000
LogP	7.29300
Vapour Pressure	4.79E-21mmHg at 25°C
Index of Refraction	1.633
Storage condition	-20°C

Osanetant MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
RIDADR	NONH for all modes of transport

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Osanetant
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Osanetant
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Osanetant
Price: $950.0/100mg $1750.0/250mg $3500.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: ￥2600/1 mg

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Osanetant

Use of Osanetant

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Osanetant Biological Activity

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