KBP-7018

Modify Date: 2024-09-18 10:59:36

KBP-7018 Structure
KBP-7018 structure
Common Name KBP-7018
CAS Number 1613437-66-3 Molecular Weight 538.604
Density N/A Boiling Point N/A
Molecular Formula C31H30N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KBP-7018


A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).

 Names

Name KBP-7018

 KBP-7018 Biological Activity

Description A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).
References References 1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147. 2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28. View Related Products by Target c-Kit

 Chemical & Physical Properties

Molecular Formula C31H30N4O5
Molecular Weight 538.604